Paper

Inhibition of FAM19A5 reverses synaptic loss and cognitive decline in mouse models of Alzheimer's disease (2025) Alzheimer's Research and Therapy; https://doi.org/10.1186/s13195-025-01813-8. Kim, Han-Byul, Yoo, Sangjin, Kwak, Hoyun, Ma, Shi-Xun, Kim, Ryunhee, Lee, Minhyeok, Ha, Nui, Pyo, Soonil, Kwon, Soon-Gu, Cho, Eun-Ho, Lee, Sang-Myeong, Jang, Juwon, Kim, Won Kyum, Park, Hae-Chul, Baek, Minkyung, Park, Yosub, Park, Ji-Young, Park, Jin-Woo, Hwang, Sun Wook, Hwang, Jong-Ik, Seong, Jae Young

Revealing the role of increased SK3 expression in sulfonylurea resistance triggered by prolonged exposure (2025) Nutrition and Diabetes; https://doi.org/10.1038/s41387-025-00384-9. Park, Jung Gyu, Kim, Minseok, Yoo, Sungje, Hwang, Sun Wook, Mok, Jongsoo, Park, Joonghoon, Kang, Keon Wook

Discovery of Dual TRPA1 and TRPV1 Antagonists as Novel Therapeutic Agents for Pain (2024) Pharmaceuticals; https://doi.org/10.3390/ph17091209. Do, Nayeon, Zuo, Dongxu, Kim, Miri, Kim, Minseok, Ha, Hee-Jin, Blumberg, Peter M., Ann, Jihyae, Hwang, Sun Wook, Lee, Jeewoo

FGF4 and ascorbic acid enhance the maturation of induced cardiomyocytes by activating JAK2-STAT3 signaling (2024) Experimental & Molecular Medicine; https://doi.org/10.1038/s12276-024-01321-z. Jun, Seongmin, Song, Myeong-Hwa, Choi, Seung-Cheol, Noh, Ji-Min, Kim, Kyung Seob, Park, Jae Hyoung, Yoon, Da Eun, Kim, Kyoungmi, Kim, Minseok, Hwang, Sun Wook, Lim, Do-Sun

FGF4 and ascorbic acid enhance the maturation of induced cardiomyocytes by activating JAK2–STAT3 signaling (2024) Experimental & Molecular Medicine; https://doi.org/10.1038/s12276-024-01321-z. Seongmin Jun, Myeong-Hwa Song, Seung-Cheol Choi, Ji-Min Noh, Kyung Seob Kim, Jae Hyoung Park, Da Eun Yoon, Kyoungmi Kim, Minseok Kim, Sun Wook Hwang, Do-Sun Lim

Discovery of Dual TRPA1 and TRPV1 Antagonists as Novel Therapeutic Agents for Pain (2024) Pharmaceuticals; https://doi.org/10.3390/ph17091209. Nayeon Do, Dongxu Zuo, Miri Kim, Minseok Kim, Hee-Jin Ha, Peter M. Blumberg, Jihyae Ann, Sun Wook Hwang, Jeewoo Lee

Pharmacologic inhibition of Il6st/gp130 improves dermatological inflammation and pruritus (2024) Biomedicine & Pharmacotherapy; https://doi.org/10.1016/j.biopha.2024.117155. Kim, Minseok, Kim, Chaeeun, Zheng, Haiyan, Kim, Yerin, Cho, Pyung Sun, Lim, Ji Yeon, Choi, WonSeok, Kim, Miri, Kim, Yebeen, Kim, Hong-Rae, Lee, Gi Young, Hwang, Sun Wook

GnRH peripherally modulates nociceptor functions, exacerbating mechanical pain (2024) Frontiers in Molecular Neuroscience; https://doi.org/10.3389/fnmol.2024.1160435. Zheng, Haiyan, Kim, Minseok, Kim, Chaeun, Kim, Yerin, Cho, Pyung Sun, Lim, Ji Yeon, Lee, Hojin, Yun, Hye-In, Choi, Jungmin, Hwang, Sun Wook

Pamoic acid-induced peripheral GPR35 activation improves pruritus and dermatitis (2023) British Journal of Pharmacology; https://doi.org/10.1111/bph.16201. Kim, Chaeeun, Kim, Yerin, Lim, Ji Yeon, Kim, Minseok, Zheng, Haiyan, Kim, Miri, Hwang, Sun Wook

Pamoic acid‐induced peripheral GPR35 activation improves pruritus and dermatitis (2023) British Journal of Pharmacology; https://doi.org/10.1111/bph.16201. Chaeeun Kim, Yerin Kim, Ji Yeon Lim, Minseok Kim, Haiyan Zheng, Miri Kim, Sun Wook Hwang

TRPV1 inhibition overcomes cisplatin resistance by blocking autophagy-mediated hyperactivation of EGFR signaling pathway (2023) NATURE COMMUNICATIONS; https://doi.org/10.1038/s41467-023-38318-7. Oh, Se Jin, Lim, Ji Yeon, Son, Min Kyu, Ahn, Jun Hyeok, Song, Kwon-Ho, Lee, Hyo-Jung, Kim, Suyeon, Cho, Eun Ho, Chung, Joon-Yong, Cho, Hanbyoul, Kim, Hyosun, Kim, Jae-Hoon, Park, Jooyoung, Choi, Jungmin, Hwang, Sun Wook, Kim, Tae Woo

Gpr83 Tunes Nociceptor Function, Controlling Pain (2023) Neurotherapeutics; https://doi.org/10.1007/s13311-022-01327-3. Yerin Kim, Chaeeun Kim, Hojin Lee, Minseok Kim, Haiyan Zheng, Ji Yeon Lim, Hye-In Yun, Minji Jeon, Jungmin Choi, Sun Wook Hwang

Drosophila ppk19 encodes a proton-gated and mechanosensitive ion channel (2022) Scientific Reports; https://doi.org/10.1038/s41598-022-23236-3. Jang, Wijeong, Lim, Ji Yeon, Kang, Seyoung, Kim, Minseok, Hwang, Sun Wook, Kim, Changsoo

Drosophila ppk19 encodes a proton-gated and mechanosensitive ion channel (2022) Scientific Reports; https://doi.org/10.1038/s41598-022-23236-3. Sun Wook Hwang, Wijeong Jang, Ji Yeon Lim, Seyoung Kang, Minseok Kim, Sun Wook Hwang, Changsoo Kim

Gpr83 Tunes Nociceptor Function, Controlling Pain (2022) Neurotherapeutics; https://doi.org/10.1007/s13311-022-01327-3. Kim, Yerin, Kim, Chaeeun, Lee, Hojin, Kim, Minseok, Zheng, Haiyan, Lim, Ji Yeon, Yun, Hye-In, Jeon, Minji, Choi, Jungmin, Hwang, Sun Wook

Senolytic drugs relieve pain by reducing peripheral nociceptive signaling without modifying joint tissue damage in spontaneous osteoarthritis (2022) Aging-us; https://doi.org/10.18632/aging.204204. Gil, Tae-Hwan, Zheng, Haiyan, Lee, Hyo Gyeong, Shin, Ji-Won, Hwang, Sun Wook, Jang, Ki-Mo, Jeon, Ok Hee

The role of oxytocin, vasopressin, and their receptors at nociceptors in peripheral pain modulation (2021) Frontiers in Neuroendocrinology; https://doi.org/10.1016/j.yfrne.2021.100942. Zheng, Haiyan, Lim, Ji Yeon, Kim, Yerin, Jung, Sang Taek, Hwang, Sun Wook

FAM19A5l Affects Mustard Oil-Induced Peripheral Nociception in Zebrafish (2021) MOLECULAR NEUROBIOLOGY; https://doi.org/10.1007/s12035-021-02449-z. Jeong, In Young, Yun, Seongsik, Shahapal, Anu, Cho, Eun Bee, Hwang, Sun Wook, Seong, Jae Young, Park, Hae-Chul

GPR171 Activation Modulates Nociceptor Functions, Alleviating Pathologic Pain (2021) BIOMEDICINES; https://doi.org/10.3390/biomedicines9030256. Cho, Pyung Sun, Lee, Han Kyu, Choi, Young In, Choi, Seung In, Lim, Ji Yeon, Kim, Minseok, Kim, Hyun, Jung, Sung Jun, Hwang, Sun Wook

GPR171 Activation Modulates Nociceptor Functions, Alleviating Pathologic Pain (2021) Biomedicines; https://doi.org/10.3390/biomedicines9030256. Pyung Sun Cho, Han Kyu Lee, Young In Choi, Seung In Choi, Ji Yeon Lim, Minseok Kim, Hyun Kim, Sung Jun Jung, Sun Wook Hwang

The Role of Corticotropin-Releasing Hormone at Peripheral Nociceptors: Implications for Pain Modulation (2020) BIOMEDICINES; https://doi.org/10.3390/biomedicines8120623. Zheng, Haiyan, Lim, Ji Yeon, Seong, Jae Young, Hwang, Sun Wook

Molecular mechanisms underlying the actions of arachidonic acid-derived prostaglandins on peripheral nociception (2020) JOURNAL OF NEUROINFLAMMATION; https://doi.org/10.1186/s12974-020-1703-1. Jang, Yongwoo, Kim, Minseok, Hwang, Sun Wook

Discovery of Nonpungent Transient Receptor Potential Vanilloid 1 (TRPV1) Agonist as Strong Topical Analgesic (2020) JOURNAL OF MEDICINAL CHEMISTRY; https://doi.org/10.1021/acs.jmedchem.9b01046. Ann, Jihyae, Kim, Ho Shin, Thorat, Shivaji A., Kim, Hee, Ha, Hee-Jin, Choi, Kwanghyun, Kim, Young-Ho, Kim, Minseok, Hwang, Sun Wook, Pearce, Larry, V, Esch, Timothy E., Turcios, Noe A., Blumberg, Peter M., Lee, Jeewoo

The Role of Corticotropin-Releasing Hormone at Peripheral Nociceptors: Implications for Pain Modulation (2020) Biomedicines; https://doi.org/10.3390/biomedicines8120623. Haiyan Zheng, Ji Yeon Lim, Jae Young Seong, Sun Wook Hwang

Molecular mechanisms underlying the actions of arachidonic acid-derived prostaglandins on peripheral nociception (2020) Journal of neuroinflammation; https://doi.org/10.1186/s12974-020-1703-1. Jang, Y., Kim, M., Hwang, S.W.

Molecular mechanisms underlying the actions of arachidonic acid-derived prostaglandins on peripheral nociception (2020) Journal of Neuroinflammation; https://doi.org/10.1186/s12974-020-1703-1. Yongwoo Jang, Minseok Kim, Sun Wook Hwang

Impairment of proprioceptive movement and mechanical nociception in Drosophila melanogaster larvae lacking Ppk30, a Drosophila member of the Degenerin/Epithelial Sodium Channel family (2019) GENES BRAIN AND BEHAVIOR; https://doi.org/10.1111/gbb.12545. Jang, Wijeong, Lee, Sojung, Choi, Seung-In, Chae, Hyo-Seok, Han, Jisun, Jo, Heeji, Hwang, Sun W., Park, Chul-Seung, Kim, Changsoo

TRPV4-Mediated Anti-nociceptive Effect of Suberanilohydroxamic Acid on Mechanical Pain (2019) MOLECULAR NEUROBIOLOGY; https://doi.org/10.1007/s12035-018-1093-x. Choi, Geunyeol, Yang, Tae-Jin, Yoo, Sungjae, Choi, Seung-In, Lim, Ji Yeon, Cho, Pyung Sun, Hwang, Sun Wook

Discovery of Nonpungent Transient Receptor Potential Vanilloid 1 (TRPV1) Agonist as Strong Topical Analgesic (2019) Journal of Medicinal Chemistry; https://doi.org/10.1021/acs.jmedchem.9b01046. Ann, J., Kim, H.S., Thorat, S.A., Kim, H., Ha, H.-J., Choi, K., Kim, Y.-H., Kim, M., Hwang, S.W., Pearce, L.V., Esch, T.E., Turcios, N.A., Blumberg, P.M., Lee, J.

TRPV4-Mediated Anti-nociceptive Effect of Suberanilohydroxamic Acid on Mechanical Pain (2019) Molecular Neurobiology; https://doi.org/10.1007/s12035-018-1093-x. Choi, G., Yang, T.-J., Yoo, S., Choi, S.-I., Lim, J.Y., Cho, P.S., Hwang, S.W.

Impairment of proprioceptive movement and mechanical nociception in Drosophila melanogaster larvae lacking Ppk30, a Drosophila member of the Degenerin/Epithelial Sodium Channel family (2019) Genes, Brain and Behavior; https://doi.org/10.1111/gbb.12545. Jang, W., Lee, S., Choi, S.-I., Chae, H.-S., Han, J., Jo, H., Hwang, S.W., Park, C.-S., Kim, C.

TRPV4-Mediated Anti-nociceptive Effect of Suberanilohydroxamic Acid on Mechanical Pain (2019) Molecular Neurobiology; https://doi.org/10.1007/s12035-018-1093-x. Geunyeol Choi, Tae-Jin Yang, Sungjae Yoo, Seung-In Choi, Ji Yeon Lim, Pyung Sun Cho, Sun Wook Hwang

Nociceptive Roles of TRPM2 Ion Channel in Pathologic Pain (2018) MOLECULAR NEUROBIOLOGY; https://doi.org/10.1007/s12035-017-0862-2. Jang, Yongwoo, Cho, Pyung Sun, Yang, Young Duk, Hwang, Sun Wook

Romo1 is a mitochondrial nonselective cation channel with viroporin-like characteristics (2018) JOURNAL OF CELL BIOLOGY; https://doi.org/10.1083/jcb.201709001. Lee, Gi Young, You, Deok-gyun, Lee, Hye-Ra, Hwang, Sun Wook, Lee, C. Justin, Yoo, Young Do

Depolarizing Effectors of Bradykinin Signaling in Nociceptor Excitation in Pain Perception (2018) BIOMOLECULES & THERAPEUTICS; https://doi.org/10.4062/biomolther.2017.127. Choi, Seung-In, Hwang, Sun Wook

Peripheral serotonin receptor 2B and transient receptor potential channel 4 mediate pruritus to serotonergic anti-depressants in mice (2018) JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY; https://doi.org/10.1016/j.jaci.2018.05.031. Lee, Sang Hoon, Cho, Pyung Sun, Tonello, Raquel, Lee, Han Kyu, Jang, Jun Ho, Park, Gi Yeon, Hwang, Sun Wook, Park, Chul-Kyu, Jung, Sung Jun, Berta, Temugin

Inhibitory effect of ethanolic extract of Ramulus mori on adipogenic differentiation of 3T3-L1 cells and their antioxidant activity (2018) JOURNAL OF FOOD BIOCHEMISTRY; https://doi.org/10.1111/jfbc.12469. Hwang, Seonwook, Kim, Jeong-Keun, Kim, In-Ho, Lim, Young-Hee

Depolarizing effectors of bradykinin signaling in nociceptor excitation in pain perception (2018) Biomolecules and Therapeutics; https://doi.org/10.4062/biomolther.2017.127. Choi, S.-I., Hwang, S.W.

Peripheral serotonin receptor 2B and transient receptor potential channel 4 mediate pruritus to serotonergic antidepressants in mice (2018) Journal of Allergy and Clinical Immunology; https://doi.org/10.1016/j.jaci.2018.05.031. Lee, S.H., Cho, P.S., Tonello, R., Lee, H.K., Jang, J.H., Park, G.Y., Hwang, S.W., Park, C.-K., Jung, S.J., Berta, T.

Nociceptive Roles of TRPM2 Ion Channel in Pathologic Pain (2018) Molecular Neurobiology; https://doi.org/10.1007/s12035-017-0862-2. Jang, Y., Cho, P.S., Yang, Y.D., Hwang, S.W.

Romo1 is a mitochondrial nonselective cation channel with viroporin-like characteristics (2018) Journal of Cell Biology; https://doi.org/10.1083/jcb.201709001. Lee, G.Y., You, D.-G., Lee, H.-R., Hwang, S.W., Justin Lee, C., Yoo, Y.D.

Peripheral serotonin receptor 2B and transient receptor potential channel 4 mediate pruritus to serotonergic antidepressants in mice (2018) Journal of Allergy and Clinical Immunology; https://doi.org/10.1016/j.jaci.2018.05.031. Sang Hoon Lee, Pyung Sun Cho, Raquel Tonello, Han Kyu Lee, Jun Ho Jang, Gi Yeon Park, Sun Wook Hwang, Chul-Kyu Park, Sung Jun Jung, Temugin Berta

Romo1 is a mitochondrial nonselective cation channel with viroporin-like characteristics (2018) The Journal of Cell Biology; https://doi.org/10.1083/jcb.201709001. Gi Young Lee, Deok-gyun You, Hye-Ra Lee, Sun Wook Hwang, C. Justin Lee, Young Do Yoo

Nociceptive Roles of TRPM2 Ion Channel in Pathologic Pain (2018) Molecular Neurobiology; https://doi.org/10.1007/s12035-017-0862-2. Yongwoo Jang, Pyung Sun Cho, Young Duk Yang, Sun Wook Hwang

Endogenous TRPV4 Expression of a Hybrid Neuronal Cell Line N18D3 and Its Utilization to Find a Novel Synthetic Ligand (2017) JOURNAL OF MOLECULAR NEUROSCIENCE; https://doi.org/10.1007/s12031-017-0993-y. Yoo, Sungjae, Choi, Seung-In, Lee, Seul, Song, Jiho, Yang, Chungmi, Bang, Sangsu, Kim, Seung Up, Min, Kyung Hoon, Hwang, Sun Wook

Heterogeneity in the Drosophila gustatory receptor complexes that detect aversive compounds (2017) NATURE COMMUNICATIONS; https://doi.org/10.1038/s41467-017-01639-5. Sung, Ha Yeon, Jeong, Yong Taek, Lim, Ji Yeon, Kim, Hyeyon, Oh, Soo Min, Hwang, Sun Wook, Kwon, Jae Young, Moon, Seok Jun

Heterogeneity in the Drosophila gustatory receptor complexes that detect aversive compounds (2017) Nature Communications; https://doi.org/10.1038/s41467-017-01639-5. Sung, H.Y., Jeong, Y.T., Lim, J.Y., Kim, H., Oh, S.M., Hwang, S.W., Kwon, J.Y., Moon, S.J.

Endogenous TRPV4 Expression of a Hybrid Neuronal Cell Line N18D3 and Its Utilization to Find a Novel Synthetic Ligand (2017) Journal of Molecular Neuroscience; https://doi.org/10.1007/s12031-017-0993-y. Yoo, S., Choi, S.-I., Lee, S., Song, J., Yang, C., Bang, S., Kim, S.U., Min, K.H., Hwang, S.W.

Heterogeneity in the Drosophila gustatory receptor complexes that detect aversive compounds (2017) Nature Communications; https://doi.org/10.1038/s41467-017-01639-5. Ha Yeon Sung, Yong Taek Jeong, Ji Yeon Lim, Hyeyon Kim, Soo Min Oh, Sun Wook Hwang, Jae Young Kwon, Seok Jun Moon

Endogenous TRPV4 Expression of a Hybrid Neuronal Cell Line N18D3 and Its Utilization to Find a Novel Synthetic Ligand (2017) Journal of Molecular Neuroscience; https://doi.org/10.1007/s12031-017-0993-y. Sungjae Yoo, Seung-In Choi, Seul Lee, Jiho Song, Chungmi Yang, Sangsu Bang, Seung Up Kim, Kyung Hoon Min, Sun Wook Hwang

Emerging Role of Spinal Cord TRPV1 in Pain Exacerbation (2016) NEURAL PLASTICITY; https://doi.org/10.1155/2016/5954890. Choi, Seung-In, Lim, Ji Yeon, Yoo, Sungjae, Kim, Hyun, Hwang, Sun Wook

Chitosan functionalized thermosponge nano-carriers for prolonged retention and local delivery of chymopapain at the nucleus pulposus in porcine discs ex vivo (2016) RSC ADVANCES; https://doi.org/10.1039/c6ra17848k. Choi, Won Il, Sahu, Abhishek, Vilos, Cristian, Lee, Jong Hyun, Kim, Sunghyun, Hong, Young Ki, Sul, Donggeun, Hwang, Sun Wook, Lee, Sang Heon, Tae, Giyoong

Atypical sensors for direct and rapid neuronal detection of bacterial pathogens (2016) MOLECULAR BRAIN; https://doi.org/10.1186/s13041-016-0202-x. Lim, Ji Yeon, Choi, Seung-In, Choi, Geunyeol, Hwang, Sun Wook

Modulation of the Activities of Neuronal Ion Channels by Fatty Acid-Derived Pro-Resolvents (2016) FRONTIERS IN PHYSIOLOGY; https://doi.org/10.3389/fphys.2016.00523. Choi, Geunyeol, Hwang, Sun Wook

P2X1 Receptor-Mediated Ca2+ Influx Triggered by DA-9801 Potentiates Nerve Growth Factor-Induced Neurite Outgrowth (2016) ACS CHEMICAL NEUROSCIENCE; https://doi.org/10.1021/acschemneuro.6b00082. Back, Moon Jung, Lee, Hae Kyung, Lee, Joo Hyun, Fu, Zhicheng, Son, Mi Won, Choi, Sang Zin, Go, Hyo Sang, Yoo, Sungjae, Hwang, Sun Wook, Kim, Dae Kyong

Chitosan functionalized thermosponge nano-carriers for prolonged retention and local delivery of chymopapain at the nucleus pulposus in porcine discs ex vivo (2016) RSC Advances; https://doi.org/10.1039/c6ra17848k. Choi, W.I., Sahu, A., Vilos, C., Lee, J.H., Kim, S., Hong, Y.K., Sul, D., Hwang, S.W., Lee, S.H., Tae, G.

Atypical sensors for direct and rapid neuronal detection of bacterial pathogens (2016) Molecular Brain; https://doi.org/10.1186/s13041-016-0202-x. Lim, J.Y., Choi, S.-I., Choi, G., Hwang, S.W.

P2X1 Receptor-Mediated Ca<sup>2+</sup> Influx Triggered by DA-9801 Potentiates Nerve Growth Factor-Induced Neurite Outgrowth (2016) ACS Chemical Neuroscience; https://doi.org/10.1021/acschemneuro.6b00082. Back, M.J., Lee, H.K., Lee, J.H., Fu, Z., Son, M.W., Choi, S.Z., Go, H.S., Yoo, S., Hwang, S.W., Kim, D.K.

Modulation of the activities of neuronal ion channels by fatty acid-derived pro-resolvents (2016) Frontiers in Physiology; https://doi.org/10.3389/fphys.2016.00523. Choi, G., Hwang, S.W.

Emerging Role of Spinal Cord TRPV1 in Pain Exacerbation (2016) Neural Plasticity; https://doi.org/10.1155/2016/5954890. Choi, S.-I., Lim, J.Y., Yoo, S., Kim, H., Hwang, S.W.

Biological Roles of Resolvins and Related Substances in the Resolution of Pain (2015) BIOMED RESEARCH INTERNATIONAL; https://doi.org/10.1155/2015/830930. Lim, Ji Yeon, Park, Chul-Kyu, Hwang, Sun Wook

Biological Roles of Resolvins and Related Substances in the Resolution of Pain (2015) BioMed Research International; https://doi.org/10.1155/2015/830930. Lim, J.Y., Park, C.-K., Hwang, S.W.

Are Sensory TRP Channels Biological Alarms for Lipid Peroxidation? (2014) INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES; https://doi.org/10.3390/ijms150916430. Choi, Seung-In, Yoo, Sungjae, Lim, Ji Yeon, Hwang, Sun Wook

Sensory TRP Channel Interactions with Endogenous Lipids and Their Biological Outcomes (2014) MOLECULES; https://doi.org/10.3390/molecules19044708. Yoo, Sungjae, Lim, Ji Yeon, Hwang, Sun Wook

Sensory TRP channel interactions with endogenous lipids and their biological outcomes (2014) Molecules; https://doi.org/10.3390/molecules19044708. Yoo, S., Lim, J.Y., Hwang, S.W.

Are sensory TRP channels biological alarms for lipid peroxidation? (2014) International Journal of Molecular Sciences; https://doi.org/10.3390/ijms150916430. Choi, S.-I., Yoo, S., Lim, J.Y., Hwang, S.W.

tmc-1 encodes a sodium-sensitive channel required for salt chemosensation in C. elegans (2013) NATURE; https://doi.org/10.1038/nature11845. Chatzigeorgiou, Marios, Bang, Sangsu, Hwang, Sun Wook, Schafer, William R.

Voluntary movements as a possible non-reflexive pain assay (2013) MOLECULAR PAIN; https://doi.org/10.1186/1744-8069-9-25. Cho, Hawon, Jang, Yongwoo, Lee, Byeongjun, Chun, Hyeyoun, Jung, Jooyoung, Kim, Sung Min, Hwang, Sun Wook, Oh, Uhtaek

Advances in Research on Pharmacological Targets for Pain Relief (2013) CURRENT NEUROPHARMACOLOGY; Hwang, Sun Wook

Resolvins: Endogenously-Generated Potent Painkilling Substances and their Therapeutic Perspectives (2013) CURRENT NEUROPHARMACOLOGY; Yoo, Sungjae, Lim, Ji Yeon, Hwang, Sun Wook

Bacteria activate sensory neurons that modulate pain and inflammation (2013) NATURE; https://doi.org/10.1038/nature12479. Chiu, Isaac M., Heesters, Balthasar A., Ghasemlou, Nader, Von Hehn, Christian A., Zhao, Fan, Tran, Johnathan, Wainger, Brian, Strominger, Amanda, Muralidharan, Sriya, Horswill, Alexander R., Wardenburg, Juliane Bubeck, Hwang, Sun Wook, Carroll, Michael C., Woolf, Clifford J.

Emerging roles of TRPA1 in sensation of oxidative stress and its implications in defense and danger (2013) ARCHIVES OF PHARMACAL RESEARCH; https://doi.org/10.1007/s12272-013-0098-2. Kim, SangSeong, Hwang, Sun Wook

Peptide neurotoxins targeting voltage-gated ion channels and their therapeutic implications (2013) FRONTIERS IN CLINICAL DRUG RESEARCH - CENTRAL NERVOUS SYSTEM; 황선욱

Pain sensor molecules of the primary afferent nerves and their nociceptive modalities (2013) ADVANCES IN MEDICINE AND BIOLOGY; 황선욱

Advances in research on pharmacological targets for pain relief (2013) Current Neuropharmacology; https://doi.org/10.2174/1570159X11311060001. Hwang, S.W.

Resolvins: Endogenously-generated potent painkilling substances and their therapeutic perspectives (2013) Current Neuropharmacology; https://doi.org/10.2174/1570159X11311060009. Yoo, S., Lim, J.Y., Hwang, S.W.

Editorial (Thematic Issue: Advances in Research on Pharmacological Targets for Pain Relief) (2013) Current Neuropharmacology; https://doi.org/10.2174/1570159x11311060001. Sun Hwang

Resolvins: Endogenously-Generated Potent Painkilling Substances and their Therapeutic Perspectives (2013) Current Neuropharmacology; https://doi.org/10.2174/1570159x11311060009. Sungjae Yoo, Ji Lim, Sun Hwang

Emerging roles of TRPA1 in sensation of oxidative stress and its implications in defense and danger (2013) Archives of Pharmacal Research; https://doi.org/10.1007/s12272-013-0098-2. Kim, S., Hwang, S.W.

Tmc-1 encodes a sodium-sensitive channel required for salt chemosensation in C. elegans (2013) Nature; https://doi.org/10.1038/nature11845. Chatzigeorgiou, M., Bang, S., Hwang, S.W., Schafer, W.R.

Voluntary movements as a possible non-reflexive pain assay (2013) Molecular Pain; https://doi.org/10.1186/1744-8069-9-25. Cho, H., Jang, Y., Lee, B., Chun, H., Jung, J., Kim, S.M., Hwang, S.W., Oh, U.

Bacteria activate sensory neurons that modulate pain and inflammation (2013) Nature; https://doi.org/10.1038/nature12479. Chiu, I.M., Heesters, B.A., Ghasemlou, N., Von Hehn, C.A., Zhao, F., Tran, J., Wainger, B., Strominger, A., Muralidharan, S., Horswill, A.R., Wardenburg, J.B., Hwang, S.W., Carroll, M.C., Woolf, C.J.

Nociceptive and pro-inflammatory effects of dimethylallyl pyrophosphate via TRPV4 activation (2012) BRITISH JOURNAL OF PHARMACOLOGY; https://doi.org/10.1111/j.1476-5381.2012.01884.x. Bang, S., Yoo, S., Yang, T. J., Cho, H., Hwang, S. W.

17(R)-resolvin D1 specifically inhibits transient receptor potential ion channel vanilloid 3 leading to peripheral antinociception (2012) BRITISH JOURNAL OF PHARMACOLOGY; https://doi.org/10.1111/j.1476-5381.2011.01568.x. Bang, S., Yoo, S., Yang, T. J., Cho, H., Hwang, S. W.

Inhibition of sensory neuronal TRPs contributes to anti-nociception by butamben (2012) NEUROSCIENCE LETTERS; https://doi.org/10.1016/j.neulet.2011.11.026. Bang, Sangsu, Yang, Tae-Jin, Yoo, Sungjae, Heo, Tae-Hwe, Hwang, Sun Wook

다양한 rhBMP-2 코팅 임플란트 표면에서의 인간 간엽 줄기세포의 부착, 증식, 분화반응 분석 (2012) 대한치과보철학회지; https://doi.org/10.4047/jkap.2012.50.1.44. 이인구, 한인호, 황선욱, 류재준

SENSORY TRP CHANNEL INTERACTION WITH LIPIDS: THEIR IMPLICATIONS IN PAIN MODULATION (2012) ADVANCES IN MEDICINE AND BIOLOGY; 황선욱

Nociceptive and Nonnociceptive Roles of TRPV3 and Its “Druggability” (2012) TRP CHANNELS IN DRUG DISCOVERY; 황선욱

Analysis of attachment, proliferation and differentiation response of human mesenchymal stem cell to various implant surfaces coated with rhBMP-2 (2012) The Journal of Korean Academy of Prosthodontics; https://doi.org/10.4047/jkap.2012.50.1.44. In-Ku Lee, In-Ho Han, Sun-Wook Hwang, Jae-Jun Ryu

Inhibition of sensory neuronal TRPs contributes to anti-nociception by butamben (2012) Neuroscience Letters; https://doi.org/10.1016/j.neulet.2011.11.026. Bang, S., Yang, T.-J., Yoo, S., Heo, T.-H., Hwang, S.W.

17(R)-resolvin D1 specifically inhibits transient receptor potential ion channel vanilloid 3 leading to peripheral antinociception (2012) British Journal of Pharmacology; https://doi.org/10.1111/j.1476-5381.2011.01568.x. Bang, S., Yoo, S., Yang, T.J., Cho, H., Hwang, S.

Nociceptive and pro-inflammatory effects of dimethylallyl pyrophosphate via TRPV4 activation (2012) British Journal of Pharmacology; https://doi.org/10.1111/j.1476-5381.2012.01884.x. Bang, S., Yoo, S., Yang, T.J., Cho, H., Hwang, S.W.

Nanoparticle Formulation for Controlled Release of Capsaicin (2011) JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY; https://doi.org/10.1166/jnn.2011.3636. Kim, Seon, Kim, Jong Chul, Sul, Donggeun, Hwang, Sun Wook, Lee, Sang Heon, Kim, Young Ha, Tae, Giyoong

Isopentenyl pyrophosphate is a novel antinociceptive substance that inhibits TRPV3 and TRPA1 ion channels (2011) PAIN; https://doi.org/10.1016/j.pain.2011.01.044. Bang, Sangsu, Yoo, Sungjae, Yang, Tae-Jin, Cho, Hawon, Hwang, Sun Wook

Nanoparticle formulation for controlled release of capsaicin (2011) Journal of Nanoscience and Nanotechnology; https://doi.org/10.1166/jnn.2011.3636. Kim, S., Kim, J.C., Sul, D., Hwang, S.W., Lee, S.H., Kim, Y.H., Tae, G.

Isopentenyl pyrophosphate is a novel antinociceptive substance that inhibits TRPV3 and TRPA1 ion channels (2011) Pain; https://doi.org/10.1016/j.pain.2011.01.044. Bang, S., Yoo, S., Yang, T.-J., Cho, H., Hwang, S.W.

Endogenous Lipid-derived Ligands for Sensory TRP Ion Channels and Their Pain Modulation (2010) ARCHIVES OF PHARMACAL RESEARCH; https://doi.org/10.1007/s12272-010-1004-9. Bang, Sangsu, Yoo, Sungjae, Oh, Uhtaek, Hwang, Sun Wook

Resolvin D1 attenuates activation of sensory transient receptor potential channels leading to multiple anti-nociception (2010) BRITISH JOURNAL OF PHARMACOLOGY; https://doi.org/10.1111/j.1476-5381.2010.00909.x. Bang, S., Yoo, S., Yang, T. J., Cho, H., Kim, Y. G., Hwang, S. W.

Laser Modulation of Heat and Capsaicin Receptor TRPV1 Leads to Thermal Antinociception (2010) JOURNAL OF DENTAL RESEARCH; https://doi.org/10.1177/0022034510381394. Ryu, J. -J., Yoo, S., Kim, K. Y., Park, J. -S., Bang, S., Lee, S. H., Yang, T. -J., Cho, H., Hwang, S. W.

Neuron-Specific Expression of atp6v0c2 in Zebrafish CNS (2010) DEVELOPMENTAL DYNAMICS; https://doi.org/10.1002/dvdy.22383. Chung, Ah-Young, Kim, Myoung-Jin, Kim, Dohyun, Bang, Sangsu, Hwang, Sun Wook, Lim, Chae Seung, Lee, Sanggyu, Park, Hae-Chul, Huh, Tae-Lin

Specific roles for DEG/ENaC and TRP channels in touch and thermosensation in C. elegans nociceptors (2010) NATURE NEUROSCIENCE; https://doi.org/10.1038/nn.2581. Chatzigeorgiou, Marios, Yoo, Sungjae, Watson, Joseph D., Lee, Wei-Hsiang, Spencer, W. Clay, Kindt, Katie S., Hwang, Sun Wook, Miller, David M., III, Treinin, Millet, Driscoll, Monica, Schafer, William R.

Farnesyl Pyrophosphate Is a Novel Pain-producing Molecule via Specific Activation of TRPV3 (2010) JOURNAL OF BIOLOGICAL CHEMISTRY; https://doi.org/10.1074/jbc.M109.087742. Bang, Sangsu, Yoo, Sungjae, Yang, Tae-Jin, Cho, Hawon, Hwang, Sun Wook

Farnesyl pyrophosphate is a novel pain-producing molecule via specific activation of TRPV3 (2010) Journal of Biological Chemistry; https://doi.org/10.1074/jbc.M109.087742. Bang, S., Yoo, S., Yang, T.-J., Cho, H., Hwang, S.W.

Laser modulation of heat and capsaicin receptor TRPV1 leads to thermal antinociception (2010) Journal of Dental Research; https://doi.org/10.1177/0022034510381394. Ryu, J.-J., Yoo, S., Kim, K.Y., Park, J.-S., Bang, S., Lee, S.H., Yang, T.-J., Cho, H., Hwang, S.W.

Neuron-specific expression of atp6v0c2 in zebrafish CNS (2010) Developmental Dynamics; https://doi.org/10.1002/dvdy.22383. Chung, A.-Y., Kim, M.-J., Kim, D., Bang, S., Hwang, S.W., Lim, C.S., Lee, S., Park, H.-C., Huh, T.-L.

Resolvin D1 attenuates activation of sensory transient receptor potential channels leading to multiple anti-nociception (2010) British Journal of Pharmacology; https://doi.org/10.1111/j.1476-5381.2010.00909.x. Bang, S., Yoo, S., Yang, T.J., Cho, H., Kim, Y.G., Hwang, S.W.

Specific roles for DEG/ENaC and TRP channels in touch and thermosensation in C. elegans nociceptors (2010) Nature Neuroscience; https://doi.org/10.1038/nn.2581. Chatzigeorgiou, M., Yoo, S., Watson, J.D., Lee, W.-H., Spencer, W.C., Kindt, K.S., Hwang, S.W., Miller, D.M., Treinin, M., Driscoll, M., Schafer, W.R.

Endogenous lipid-derived ligands for sensory TRP ion channels and their pain modulation (2010) Archives of Pharmacal Research; https://doi.org/10.1007/s12272-010-1004-9. Bang, S., Yoo, S., Oh, U., Hwang, S.W.

Polymodal Ligand Sensitivity of TRPA1 and Its Modes of Interactions (2009) JOURNAL OF GENERAL PHYSIOLOGY; https://doi.org/10.1085/jgp.200810138. Bang, Sangsu, Hwang, Sun Wook

Lipoxygenase inhibitors suppressed carrageenan-induced Fos-expression and inflammatory pain responses in the rat (2009) MOLECULES AND CELLS; https://doi.org/10.1007/s10059-009-0059-2. Yoo, Sungjae, Han, Shanshu, Park, Young Shin, Lee, Jang-Hern, Oh, Uhtaek, Hwang, Sun Wook

Comparison of growth factor and cytokine expression in patients with degenerated disc disease and herniated nucleus pulposus (2009) CLINICAL BIOCHEMISTRY; https://doi.org/10.1016/j.clinbiochem.2009.06.017. Lee, Seungcheol, Moon, Chan Sam, Sul, Donggeun, Lee, Jiyoung, Bae, Minyoung, Hong, Youngki, Lee, Min, Choi, Seonyoung, Derby, Richard, Kim, Byung-Jo, Kim, Juhan, Yoon, Joon-Sik, Wolfer, Lee, Kim, Jaemin, Wang, Joonho, Hwang, Sun-Wook, Lee, Sang-Heon

Gabapentin attenuates the activation of transient receptor potential A1 by cinnamaldehyde (2009) EXP NEUROBIOL; 황선욱

Gabapentin Attenuates the Activation of Transient Receptor Potential A1 by Cinnamaldehyde (2009) Experimental Neurobiology; https://doi.org/10.5607/en.2009.18.1.1. Sangsu Bang, Sungjae Yoo, Sun Wook Hwang

Comparison of growth factor and cytokine expression in patients with degenerated disc disease and herniated nucleus pulposus (2009) Clinical Biochemistry; https://doi.org/10.1016/j.clinbiochem.2009.06.017. Lee, S., Moon, C.S., Sul, D., Lee, J., Bae, M., Hong, Y., Lee, M., Choi, S., Derby, R., Kim, B.-J., Kim, J., Yoon, J.-S., Wolfer, L., Kim, J., Wang, J., Hwang, S.-W., Lee, S.-H.

Lipoxygenase inhibitors suppressed carrageenan-induced Fos-expression and inflammatory pain responses in the rat (2009) Molecules and Cells; https://doi.org/10.1007/s10059-009-0059-2. Yoo, S., Han, S., Park, Y.S., Lee, J.-H., Oh, U., Hwang, S.W.

Polymodal ligand sensitivity of TRPA1 and its modes of interactions (2009) Journal of General Physiology; https://doi.org/10.1085/jgp.200810138. Bang, S., Hwang, S.W.

인체의기계감각수용체의기능연구및작용약물개발 (2008) 최종보고서; 황선욱

TRP-independent inhibition of the phospholipase C pathway by natural sensory ligands (2008) BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS; https://doi.org/10.1016/j.bbrc.2008.03.077. Kim, Kyung Yoon, Bang, Sangsu, Han, Shanshu, Nguyen, Yen Hoang, Kang, Tong Mook, Kang, Keon Wook, Hwang, Sun Wook

Induction of vascular endothelial growth factor by peptidyl-prolyl isomerase Pin1 in breast cancer cells (2008) BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS; https://doi.org/10.1016/j.bbrc.2008.02.045. Kim, Mi Ra, Choi, Hong Seok, Heo, Tae-Hwe, Hwang, Sun Wook, Kang, Keon Wook

TRP-independent inhibition of the phospholipase C pathway by natural sensory ligands (2008) Biochemical and Biophysical Research Communications; https://doi.org/10.1016/j.bbrc.2008.03.077. Kim, K.Y., Bang, S., Han, S., Nguyen, Y.H., Kang, T.M., Kang, K.W., Hwang, S.W.

Induction of vascular endothelial growth factor by peptidyl-prolyl isomerase Pin1 in breast cancer cells (2008) Biochemical and Biophysical Research Communications; https://doi.org/10.1016/j.bbrc.2008.02.045. Kim, M.R., Choi, H.S., Heo, T.-H., Hwang, S.W., Kang, K.W.

ThermoTRP에 작용하는 신개념 소염진통제 후보물질 탐색 및 그 분자기전 연구 (2007) 연구결과보고서; 황선욱

TRPV 연구의 최신 동향 (2007) KOREAN SOCIETY OF MEDICAL BIOCHEMISTRY AND MOLECULAR BIOLOGY NEWS; 황선욱

An ion channel essential for sensing chemical damage (2007) JOURNAL OF NEUROSCIENCE; https://doi.org/10.1523/JNEUROSCI.3600-07.2007. Macpherson, Lindsey J., Xiao, Bailong, Kwan, Kelvin Y., Petrus, Matt J., Dubin, Adrienne E., Hwang, SunWook, Cravatt, Benjamin, Corey, David P., Patapoutian, Ardem

Transient receptor potential V2 expressed in sensory neurons is activated by probenecid (2007) NEUROSCIENCE LETTERS; https://doi.org/10.1016/j.neulet.2007.08.035. Bang, Sangsu, Kim, Kyung Yoon, Yoo, Sungjae, Lee, Sang-Heon, Hwang, Sun Wook

A role of TRPA1 in mechanical hyperalgesia is revealed by pharmacological inhibition (2007) MOLECULAR PAIN; https://doi.org/10.1186/1744-8069-3-40. Petrus, Matt, Peier, Andrea M., Bandell, Michael, Hwang, Sun Wook, Huynh, Truc, Olney, Nicholas, Jegla, Tim, Patapoutian, Ardem

Transient receptor potential A1 mediates acetaldehyde-evoked pain sensation (2007) EUROPEAN JOURNAL OF NEUROSCIENCE; https://doi.org/10.1111/j.1460-9568.2007.05882.x. Bang, Sangsu, Kim, Kyung Yoon, Yoo, Sungjae, Kim, Yoon Gyoon, Hwang, Sun Wook

Current concepts of nociception: nociceptive molecular sensors in sensory neurons (2007) CURRENT OPINION IN ANESTHESIOLOGY; https://doi.org/10.1097/ACO.0b013e3282eff91c. Hwang, Sun Wook, Oh, Uhtaek

Peripheral bee venom's anti-inflammatory effect involves activation of the coeruleospinal pathway and sympathetic preganglionic neurons (2007) NEUROSCIENCE RESEARCH; https://doi.org/10.1016/j.neures.2007.05.008. Yoon, Seo-Yeon, Kwon, Young-Bae, Kim, Hyun-Woo, Roh, Dae-Hyun, Seo, Hyoung-Sig, Han, Hojae, Lee, Hye-Jung, Beitz, Alvin J., Hwang, Sun-Wook, Lee, Jang-Hern

Peripheral bee venom's anti-inflammatory effect involves activation of the coeruleospinal pathway and sympathetic preganglionic neurons (2007) Neuroscience Research; https://doi.org/10.1016/j.neures.2007.05.008. Yoon, S.-Y., Kwon, Y.-B., Kim, H.-W., Roh, D.-H., Seo, H.-S., Han, H.-J., Lee, H.-J., Beitz, A.J., Hwang, S.-W., Lee, J.-H.

Current concepts of nociception: Nociceptive molecular sensors in sensory neurons (2007) Current Opinion in Anaesthesiology; https://doi.org/10.1097/ACO.0b013e3282eff91c. Hwang, S.W., Oh, U.

Transient receptor potential V2 expressed in sensory neurons is activated by probenecid (2007) Neuroscience Letters; https://doi.org/10.1016/j.neulet.2007.08.035. Bang, S., Kim, K.Y., Yoo, S., Lee, S.-H., Hwang, S.W.

An ion channel essential for sensing chemical damage (2007) Journal of Neuroscience; https://doi.org/10.1523/JNEUROSCI.3600-07.2007. Macpherson, L.J., Xiao, B., Kwan, K.Y., Petrus, M.J., Dubin, A.E., Hwang, S., Cravatt, B., Corey, D.P., Patapoutian, A.

A role of TRPA1 in mechanical hyperalgesia is revealed by pharmacological inhibition (2007) Molecular Pain; https://doi.org/10.1186/1744-8069-3-40. Petrus, M., Peier, A.M., Bandell, M., Hwang, S.W., Huynh, T., Olney, N., Jegla, T., Patapoutian, A.

Transient receptor potential A1 mediates acetaldehyde-evoked pain sensation (2007) European Journal of Neuroscience; https://doi.org/10.1111/j.1460-9568.2007.05882.x. Bang, S., Kim, K.Y., Yoo, S., Kim, Y.G., Hwang, S.W.

Molecular mechanisms of thermosensation (2006) THE SCRIPPS RESEARCH INSTITUTE SCIENTIFIC REPORT; 황선욱

High-throughput random mutagenesis screen reveals TRPM8 residues specifically required for activation by menthol (2006) NATURE NEUROSCIENCE; https://doi.org/10.1038/nn1665. Bandell, M, Dubin, AE, Petrus, MJ, Orth, A, Mathur, J, Hwang, SW, Patapoutian, A

TRPV1 recapitulates native capsaicin receptor in sensory neurons in association with fas-associated factor 1 (2006) JOURNAL OF NEUROSCIENCE; https://doi.org/10.1523/JNEUROSCI.4691-05.2006. Kim, S, Kang, CJ, Shin, CY, Hwang, SW, Yang, YD, Shim, WS, Park, MY, Kim, E, Kim, M, Kim, BM, Cho, HW, Shin, Y, Oh, U

High-throughput random mutagenesis screen reveals TRPM8 residues specifically required for activation by menthol (2006) Nature Neuroscience; https://doi.org/10.1038/nn1665. Bandell, M., Dubin, A.E., Petrus, M.J., Orth, A., Mathur, J., Sun, W.H., Patapoutian, A.

Molecular mechanisms of sensory neuron specification and function. (2004) THE SCRIPPS RESEARCH INSTITUTE SCIENTIFIC REPORT; 황선욱

Phosphorylation of vanilloid receptor 1 by Ca2+/calmodulin-dependent kinase II regulates its vanilloid binding (2004) JOURNAL OF BIOLOGICAL CHEMISTRY; https://doi.org/10.1074/jbc.M311448200. Jung, JY, Shin, JS, Lee, SY, Hwang, SW, Koo, J, Cho, HW, Oh, U

Ion channels - Opposite thermosensor in fruitfly and mouse (2003) NATURE; https://doi.org/10.1038/423822a. Viswanath, V, Story, GM, Peier, AM, Petrus, MJ, Hwang, SW, Patapoutian, A, Jegla, T

Agonist recognition sites in the cytosolic tails of vanilloid receptor 1 (2002) JOURNAL OF BIOLOGICAL CHEMISTRY; https://doi.org/10.1074/jbc.M207103200. Jung, J, Lee, SY, Hwang, SW, Cho, H, Shin, J, Kang, YS, Kim, S, Oh, L

Bradykinin-12-lipoxygenase-VR1 signaling pathway for inflammatory hyperalgesia (2002) PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; https://doi.org/10.1073/pnas.152002699. Shin, J, Cho, H, Hwang, SW, Jung, J, Shin, CY, Lee, SY, Kim, SH, Lee, MG, Choi, YH, Kim, J, Haber, NA, Reichling, DB, Khasar, S, Levine, JD, Oh, U

Differences in sensitivity of vanilloid receptor 1 transfected to human embryonic kidney cells and capsaicin-activated channels in cultured rat dorsal root ganglion neurons to capsaicin receptor agonists (2001) NEUROSCIENCE LETTERS; https://doi.org/10.1016/S0304-3940(00)01777-8. Shin, JS, Wang, MH, Hwang, SW, Cho, H, Cho, SY, Kwon, MJ, Lee, SY, Oh, U

Capsaicin binds to the intracellular domain of the capsaicin-activated ion channel (1999) JOURNAL OF NEUROSCIENCE; Jung, J, Hwang, SW, Kwak, J, Lee, SY, Kang, CJ, Kim, WB, Kim, D, Oh, U

Capsaicin activates a nonselective cation channel in cultured neonatal rat dorsal root ganglion neurons (1996) JOURNAL OF NEUROSCIENCE; Oh, U, Hwang, SW, Kim, DH